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Dysfunctional uterine bleeding in perimenopausal period
Dysfunctional uterine bleeding in perimenopausal period
Dr. Davari
Associate professor of TUMS
Reproductive endocrinologist
- Chronic heavy or prolonged uterine bleeding is a common gynecologic problem.
- ovulatory or anovulatory.
- Chronic heavy or prolonged uterine bleeding can result in anemia, interfere with daily activities, and raise concerns about uterine cancer.
TERMINOLOGY
- The average menstrual cycle seven days, the amount of menstrual blood loss is 35 to 40 mL per cycle.
- Menorrhagia is defined > 80 mL.
- Ovulatory or anovulatory
PREVALENCE AND IMPACT
- Approximately 10 to 35 percent of women report having menorrhagia .
- Iron deficiency anemia develops in 21 to 67 percent of cases [2,10].
- Excessive and irregular bleeding can detract from quality of life.
- Absenteeism from work or school is bothersome to many women and bleeding may also interfere with sexual activity.
Menopausal transition
- During the menopausal transition, women can also have heavy or prolonged bleeding due to uterine structural abnormalities.
- In addition, endocrine abnormalities commonly contribute to abnormal bleeding .
- In this group, intermittent anovulation often occurs and results in extended periods of estrogen production unopposed by progesterone, resulting in continued proliferation of the endometrium.
